LOC100701603 protein (Oreochromis niloticus)

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LOC100701603

NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)

Predicted Functional Partners:

sirt7

0.962

sirt6

0.959

sirt2

0.950

nadsyn1

0.940

nampt

0.939

nmnat2

0.936

rbp7

0.936

sirt4

0.933

sirt3

0.931

nadk

0.930

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100701603	nadk	ENSONIP00000012129	ENSONIP00000008318	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD kinase a.	0.930
LOC100701603	nadsyn1	ENSONIP00000012129	ENSONIP00000043141	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.940
LOC100701603	nampt	ENSONIP00000012129	ENSONIP00000048300	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.939
LOC100701603	nmnat2	ENSONIP00000012129	ENSONIP00000000357	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Nicotinamide nucleotide adenylyltransferase 2.	0.936
LOC100701603	rbp7	ENSONIP00000012129	ENSONIP00000002961	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Nicotinamide-nucleotide adenylyltransferase.	0.936
LOC100701603	sirt2	ENSONIP00000012129	ENSONIP00000020932	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.950
LOC100701603	sirt3	ENSONIP00000012129	ENSONIP00000071459	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.931
LOC100701603	sirt4	ENSONIP00000012129	ENSONIP00000018093	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.933
LOC100701603	sirt6	ENSONIP00000012129	ENSONIP00000039918	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Sirtuin 6.	0.959
LOC100701603	sirt7	ENSONIP00000012129	ENSONIP00000022389	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Sirtuin 7.	0.962
nadk	LOC100701603	ENSONIP00000008318	ENSONIP00000012129	NAD kinase a.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.930
nadk	nadsyn1	ENSONIP00000008318	ENSONIP00000043141	NAD kinase a.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.956
nadk	nmnat2	ENSONIP00000008318	ENSONIP00000000357	NAD kinase a.	Nicotinamide nucleotide adenylyltransferase 2.	0.954
nadk	rbp7	ENSONIP00000008318	ENSONIP00000002961	NAD kinase a.	Nicotinamide-nucleotide adenylyltransferase.	0.946
nadk	sirt2	ENSONIP00000008318	ENSONIP00000020932	NAD kinase a.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.927
nadk	sirt3	ENSONIP00000008318	ENSONIP00000071459	NAD kinase a.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.927
nadk	sirt4	ENSONIP00000008318	ENSONIP00000018093	NAD kinase a.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.927
nadk	sirt6	ENSONIP00000008318	ENSONIP00000039918	NAD kinase a.	Sirtuin 6.	0.927
nadk	sirt7	ENSONIP00000008318	ENSONIP00000022389	NAD kinase a.	Sirtuin 7.	0.927
nadsyn1	LOC100701603	ENSONIP00000043141	ENSONIP00000012129	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.940

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