STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgef4Uncharacterized protein. (653 aa)    
Predicted Functional Partners:
apc2
APC regulator of WNT signaling pathway 2.
   
 0.959
RAC2
Rac family small GTPase 2.
    
 0.952
LOC100696401
Ras-related C3 botulinum toxin substrate 1-like.
    
 0.952
RAC1
Rac family small GTPase 1.
    
 0.952
LOC100701814
Spermatogenesis associated 13.
  
  
 
0.901
cdc42
Cell division cycle 42.
    
 0.760
gabra2
Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 
 0.636
ENSONIP00000000682
Intersectin 2a.
    
0.563
I3KKD0_ORENI
Intersectin 2b.
    
0.563
LOC100705444
Uncharacterized protein.
    
 0.558
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.