Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plag1Pleiomorphic adenoma gene 1. (477 aa)    
Predicted Functional Partners:
ntrk3
Tyrosine-protein kinase receptor.
    
 0.715
NFIB
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.707
eif2ak3
Eukaryotic translation initiation factor 2-alpha kinase 3.
    
 0.636
LOC100695871
Caudal type homeobox 1a.
    
 
 0.629
LOC100699280
Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.629
tcf7
Transcription factor 7.
    
 
 0.586
LOC100703725
Tyrosine-protein kinase receptor.
    
 0.566
ETV6
ETS variant 6.
    
 
 0.560
slitrk6
SLIT and NTRK-like family, member 6.
    
 0.542
htt
Huntingtin.
    
 0.532
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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