Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC102081358Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1105 aa)    
Predicted Functional Partners:
pkp2
Plakophilin-2 isoform X1.
   
 0.986
I3KBL3_ORENI
Plakophilin 1b.
   
 0.982
PKP1
Plakophilin 1.
   
 0.981
LOC100707214
Junction plakoglobin a.
   
 0.973
LOC100701331
Uncharacterized protein.
   
 0.973
dsp
Desmoplakin a.
   
 0.950
LOC100703660
Desmoplakin.
   
 0.950
I3JRJ3_ORENI
Keratin 5; Belongs to the intermediate filament family.
   
 0.924
LOC100702817
Keratin 8; Belongs to the intermediate filament family.
   
 
 0.919
LOC100702519
Zgc:158846; Belongs to the intermediate filament family.
   
 
  0.917
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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