STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSC1Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (898 aa)    
Predicted Functional Partners:
pkp2
Plakophilin-2 isoform X1.
   
 0.896
I3KBL3_ORENI
Plakophilin 1b.
   
 0.845
PKP1
Plakophilin 1.
   
 0.844
LOC100707214
Junction plakoglobin a.
   
 0.835
LOC100701331
Uncharacterized protein.
   
 0.835
PKP3
Plakophilin 3a.
   
 0.827
dsp
Desmoplakin a.
   
 0.791
LOC100703660
Desmoplakin.
   
 0.791
ppl
Periplakin.
   
 0.777
I3JL62_ORENI
Uncharacterized protein.
  
0.768
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.