paxip1 protein (Oreochromis niloticus) - STRING interaction network

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paxip1

PAX interacting (with transcription-activation domain) protein 1. (1095 aa)

Predicted Functional Partners:

rbbp5

0.957

pagr1

0.954

atm

0.949

tp53bp1

0.949

rnf8

0.943

ash2l

0.938

ncoa6

0.935

brca1

0.934

nbn

0.931

wdr5

0.922

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ash2l	ncoa6	ENSONIP00000014499	ENSONIP00000059368	Ash2 like, histone lysine methyltransferase complex subunit.	Nuclear receptor coactivator 6.	0.995
ash2l	pagr1	ENSONIP00000014499	ENSONIP00000014434	Ash2 like, histone lysine methyltransferase complex subunit.	PAXIP1 associated glutamate-rich protein 1.	0.964
ash2l	paxip1	ENSONIP00000014499	ENSONIP00000012183	Ash2 like, histone lysine methyltransferase complex subunit.	PAX interacting (with transcription-activation domain) protein 1.	0.938
ash2l	rbbp5	ENSONIP00000014499	ENSONIP00000000597	Ash2 like, histone lysine methyltransferase complex subunit.	Retinoblastoma binding protein 5.	0.999
ash2l	tp53bp1	ENSONIP00000014499	ENSONIP00000008851	Ash2 like, histone lysine methyltransferase complex subunit.	Tumor protein p53 binding protein, 1.	0.778
ash2l	wdr5	ENSONIP00000014499	ENSONIP00000016443	Ash2 like, histone lysine methyltransferase complex subunit.	WD repeat domain 5.	0.999
atm	brca1	ENSONIP00000006906	ENSONIP00000020556	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.999
atm	nbn	ENSONIP00000006906	ENSONIP00000007817	Non-specific serine/threonine protein kinase.	Nibrin.	0.999
atm	paxip1	ENSONIP00000006906	ENSONIP00000012183	Non-specific serine/threonine protein kinase.	PAX interacting (with transcription-activation domain) protein 1.	0.949
atm	rnf8	ENSONIP00000006906	ENSONIP00000007491	Non-specific serine/threonine protein kinase.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.860
atm	tp53bp1	ENSONIP00000006906	ENSONIP00000008851	Non-specific serine/threonine protein kinase.	Tumor protein p53 binding protein, 1.	0.996
brca1	atm	ENSONIP00000020556	ENSONIP00000006906	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.999
brca1	nbn	ENSONIP00000020556	ENSONIP00000007817	Uncharacterized protein.	Nibrin.	0.993
brca1	paxip1	ENSONIP00000020556	ENSONIP00000012183	Uncharacterized protein.	PAX interacting (with transcription-activation domain) protein 1.	0.934
brca1	rnf8	ENSONIP00000020556	ENSONIP00000007491	Uncharacterized protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.855
brca1	tp53bp1	ENSONIP00000020556	ENSONIP00000008851	Uncharacterized protein.	Tumor protein p53 binding protein, 1.	0.998
nbn	atm	ENSONIP00000007817	ENSONIP00000006906	Nibrin.	Non-specific serine/threonine protein kinase.	0.999
nbn	brca1	ENSONIP00000007817	ENSONIP00000020556	Nibrin.	Uncharacterized protein.	0.993
nbn	paxip1	ENSONIP00000007817	ENSONIP00000012183	Nibrin.	PAX interacting (with transcription-activation domain) protein 1.	0.931
nbn	rnf8	ENSONIP00000007817	ENSONIP00000007491	Nibrin.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.907