Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tomm70Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (579 aa)    
Predicted Functional Partners:
tomm22
Translocase of outer mitochondrial membrane 22 homolog (yeast).
   
 0.999
TOMM7
Mitochondrial import receptor subunit TOM7 homolog.
    
 0.998
Prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.997
tomm6
Mitochondrial import receptor subunit TOM6 homolog.
    
 0.993
LOC100707887
Mitochondrial import receptor subunit TOM5 homolog isoform X2.
    
 0.993
TOMM20
Translocase of outer mitochondrial membrane 20.
   
 0.986
LOC100703030
Translocase of outer mitochondrial membrane 20b.
   
 0.986
LOC100696843
Translocase of outer mitochondrial membrane 40 homolog (yeast).
   
 0.982
pink1
PTEN induced kinase 1.
    
 0.981
TOMM40L
Translocase of outer mitochondrial membrane 40 like.
   
 0.972
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.