Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
COL21A1-2Collagen type XXI alpha 1 chain. (744 aa)    
Predicted Functional Partners:
I3KEZ4_ORENI
Collagen, type VI, alpha 1.
  
 
0.509
pmpcb
Peptidase (mitochondrial processing) beta; Belongs to the peptidase M16 family.
    
 
 0.474
LOC100696844
Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family.
     
 0.468
I3K487_ORENI
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
 0.468
SGPP2
Sphingosine-1-phosphate phosphatase 2.
    
 0.468
dnajc2
DnaJ (Hsp40) homolog, subfamily C, member 2.
     
 0.468
LOC100705061
Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family.
     
 0.468
VPS13B
Vacuolar protein sorting 13 homolog B.
   
  
 0.460
LOC100703340
Leucine rich repeat containing 75Ba.
      
 0.458
LOC109204494
Gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase.
   
 
 0.457
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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