Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000012226Granulin a. (1456 aa)    
Predicted Functional Partners:
Endog
Endonuclease.
      
 0.708
LOC100696864
Sortilin.
    
 
 0.646
Sort1
Sortilin.
    
 
 0.646
LOC100707775
Si:ch211-212k18.7.
   
 
 0.608
glrx3
Glutaredoxin 3.
    
 
 0.566
wfikkn1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1.
      
 0.557
I3JZY8_ORENI
Sortilin.
    
 
 0.550
psap
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
   
 0.539
LOC100704001
Surfactant protein Bb.
   
 0.539
ENSONIP00000052170
Cathepsin B.
   
 0.533
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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