ZNF521 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZNF521

Zinc finger protein 521. (1381 aa)

Predicted Functional Partners:

LOC102080858

0.655

usp7

0.622

LOC100708236

0.603

LOC100701661

0.603

EIF3S5

0.597

LOC100706337

0.575

LOC100711479

0.575

Snd1

0.575

LOC100695351

0.575

znf536

0.558

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF3S5	Snd1	ENSONIP00000045699	ENSONIP00000072484	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.	0.696
EIF3S5	ZNF521	ENSONIP00000045699	ENSONIP00000012233	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Zinc finger protein 521.	0.597
EIF3S5	usp7	ENSONIP00000045699	ENSONIP00000019747	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.697
LOC100695351	LOC100701661	ENSONIP00000079377	ENSONIP00000065913	Retinoblastoma binding protein 4, like.	Methyl-CpG-binding domain protein 3 isoform X1.	0.848
LOC100695351	LOC100708236	ENSONIP00000079377	ENSONIP00000015903	Retinoblastoma binding protein 4, like.	Methyl-CpG binding domain protein 2.	0.848
LOC100695351	LOC102080858	ENSONIP00000079377	ENSONIP00000052428	Retinoblastoma binding protein 4, like.	Zinc finger protein 219.	0.483
LOC100695351	ZNF521	ENSONIP00000079377	ENSONIP00000012233	Retinoblastoma binding protein 4, like.	Zinc finger protein 521.	0.575
LOC100695351	usp7	ENSONIP00000079377	ENSONIP00000019747	Retinoblastoma binding protein 4, like.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.473
LOC100695351	znf536	ENSONIP00000079377	ENSONIP00000053293	Retinoblastoma binding protein 4, like.	Zinc finger protein 536.	0.483
LOC100701661	LOC100695351	ENSONIP00000065913	ENSONIP00000079377	Methyl-CpG-binding domain protein 3 isoform X1.	Retinoblastoma binding protein 4, like.	0.848
LOC100701661	LOC100706337	ENSONIP00000065913	ENSONIP00000038174	Methyl-CpG-binding domain protein 3 isoform X1.	WD_REPEATS_REGION domain-containing protein.	0.848
LOC100701661	LOC100711479	ENSONIP00000065913	ENSONIP00000070642	Methyl-CpG-binding domain protein 3 isoform X1.	Retinoblastoma binding protein 4.	0.848
LOC100701661	LOC102080858	ENSONIP00000065913	ENSONIP00000052428	Methyl-CpG-binding domain protein 3 isoform X1.	Zinc finger protein 219.	0.463
LOC100701661	ZNF521	ENSONIP00000065913	ENSONIP00000012233	Methyl-CpG-binding domain protein 3 isoform X1.	Zinc finger protein 521.	0.603
LOC100701661	znf536	ENSONIP00000065913	ENSONIP00000053293	Methyl-CpG-binding domain protein 3 isoform X1.	Zinc finger protein 536.	0.463
LOC100706337	LOC100701661	ENSONIP00000038174	ENSONIP00000065913	WD_REPEATS_REGION domain-containing protein.	Methyl-CpG-binding domain protein 3 isoform X1.	0.848
LOC100706337	LOC100708236	ENSONIP00000038174	ENSONIP00000015903	WD_REPEATS_REGION domain-containing protein.	Methyl-CpG binding domain protein 2.	0.848
LOC100706337	LOC102080858	ENSONIP00000038174	ENSONIP00000052428	WD_REPEATS_REGION domain-containing protein.	Zinc finger protein 219.	0.483
LOC100706337	ZNF521	ENSONIP00000038174	ENSONIP00000012233	WD_REPEATS_REGION domain-containing protein.	Zinc finger protein 521.	0.575
LOC100706337	usp7	ENSONIP00000038174	ENSONIP00000019747	WD_REPEATS_REGION domain-containing protein.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.473