Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100711555Potassium voltage-gated channel, shaker-related subfamily, member 7; Belongs to the potassium channel family. (539 aa)    
Predicted Functional Partners:
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  0.793
I3JM39_ORENI
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.618
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.583
rpl21
Ribosomal protein L21.
   
 0.573
Rpl34
Large subunit ribosomal protein L34e.
  
 0.568
rpl29
60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.
   
 0.566
rpl30
Ribosomal protein L30.
   
 0.565
rpl31
Ribosomal protein L31.
   
 0.565
rpl13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
   
 0.558
rpl24
Ribosomal protein L24.
   
 0.556
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.