Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
LOC100711823Amino acid transporter. (668 aa)    
Predicted Functional Partners:
Slc7a5
Solute carrier family 7 member 5.
   
 
 0.757
blmh
Bleomycin hydrolase; Belongs to the peptidase C1 family.
      
 0.709
med19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.695
LOC100708101
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
    
 0.694
LOC100696665
Proteolipid protein 1b.
   
 
 0.680
ENSONIP00000068708
Myelin proteolipid protein isoform X1.
   
 
 0.680
Slc3a1
Solute carrier family 3 member 1.
   
 
 0.634
slc38a9
Solute carrier family 38 member 9.
      
 0.628
LOC100708943
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
    
 0.612
htt
Huntingtin.
   
 
 0.596
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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