Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (529 aa)    
Predicted Functional Partners:
vta1
Vesicle (multivesicular body) trafficking 1.
   
 0.982
chmp2a
Charged multivesicular body protein 2A.
    
 0.972
chmp3
Charged multivesicular body protein 3.
   
 0.967
chmp2b
Charged multivesicular body protein 2Bb.
   
 0.960
chmp1a
Charged multivesicular body protein 1A.
   
 0.959
I3J4H0_ORENI
IST1 factor associated with ESCRT-III.
   
 0.952
LOC100702665
Uncharacterized protein.
   
 0.931
chmp1b
Chromatin modifying protein 1B.
   
 0.931
LOC100710999
Charged multivesicular body protein 5b.
   
 0.924
LOC100709386
Charged multivesicular body protein 5a.
   
 0.924
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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