Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100709044Si:dkey-103j14.5. (310 aa)    
Predicted Functional Partners:
asns
Asparagine synthetase [glutamine-hydrolyzing].
     
 0.934
LOC100705311
Aspartate aminotransferase.
   
 
 0.925
cad
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.
    
 0.923
Ftcd
Formimidoyltransferase cyclodeaminase.
     
 0.922
gad2
Glutamate decarboxylase 2.
     
 0.922
adss1
Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
    
  0.921
I3J047_ORENI
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
    
  0.921
LOC100712052
Uncharacterized protein.
     
 0.919
ASS1
Argininosuccinate synthase 1.
     
 0.918
aspa
Aspartoacylase.
   
 
  0.917
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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