Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lmbrd1LMBR1 domain containing 1. (538 aa)    
Predicted Functional Partners:
abcd4
ATP-binding cassette, sub-family D (ALD), member 4.
    
 0.996
mmaa
Metabolism of cobalamin associated A.
      
 0.907
Mmab
Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
      
 0.888
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
      
 0.837
abcd3
ATP-binding cassette, sub-family D (ALD), member 3a.
    
 0.808
atraid
All-trans retinoic acid-induced differentiation factor.
      
 0.789
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.773
mmachc
Metabolism of cobalamin associated C.
      
 0.768
mmut
Methylmalonyl CoA mutase.
      
 0.759
LOC100694085
Uncharacterized protein.
      
 0.735
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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