Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tbc1d22aTBC1 domain family, member 22a. (572 aa)    
Predicted Functional Partners:
acbd3
Acyl-Coenzyme A binding domain containing 3.
    
 
 0.861
mrps9
Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
 
 0.778
mrps5
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
   
   0.764
mrps16
Mitochondrial ribosomal protein S16.
    
   0.760
dap3
Death associated protein 3.
    
   0.757
Mrps6
Mitochondrial ribosomal protein S6.
    
   0.757
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
   0.757
rps18
Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family.
    
 
 0.709
cog8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
   0.690
arfrp1
ADP-ribosylation factor related protein 1.
   
   0.676
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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