STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsd3b7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (366 aa)    
Predicted Functional Partners:
LOC100709377
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.958
CYP8B1
Cytochrome P450, family 8, subfamily B, polypeptide 2; Belongs to the cytochrome P450 family.
   
 0.956
LOC109195683
5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase.
   
 0.956
LOC109195682
5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase-like.
   
 0.956
AKR1D1
Aldo-keto reductase family 1 member D1.
  
 
 0.909
LOC109194203
Aldo_ket_red domain-containing protein.
  
 
 0.909
LOC100702293
Cytochrome P450, family 51; Belongs to the cytochrome P450 family.
   
 0.899
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.893
Sqle
Squalene epoxidase a.
   
 
 0.889
LOC100690152
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.875
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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