Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdc20Cell division cycle 20 homolog. (544 aa)    
Predicted Functional Partners:
pttg1
Uncharacterized protein.
   
 0.998
cdc27
Cell division cycle 27.
   
 0.996
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.996
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.994
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.994
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 0.992
LOC100692470
Cyclin B2; Belongs to the cyclin family.
   
 0.992
Cntd2
Cyclin N-terminal domain containing 2; Belongs to the cyclin family.
   
 0.990
nek2
NIMA-related kinase 2.
   
 0.990
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 0.990
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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