Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)    
Predicted Functional Partners:
erlec1
Endoplasmic reticulum lectin 1.
      
 0.844
psme4
Proteasome activator subunit 4a.
      
 0.770
Ptprh
Protein tyrosine phosphatase receptor type H.
      
 0.730
thbs2
Thrombospondin 2a.
      
 0.714
kcnk18
Potassium channel, subfamily K, member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
 0.696
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.684
asz1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
      
 0.674
fbxo11
Uncharacterized protein.
      
 0.665
prph2
Peripherin 2a (retinal degeneration, slow).
      
 0.646
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
 0.630
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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