LOC100707238 protein (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC100707238

BCL2 family apoptosis regulator BOK b. (213 aa)

Predicted Functional Partners:

bad

0.733

Bcl2l11

0.715

morn3

0.630

becn1

0.624

lrguk

0.606

fzd4

0.587

bmf

0.543

apaf1

0.515

LOC100696271

0.492

LOC100692041

0.492

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcl2l11	LOC100707238	ENSONIP00000042858	ENSONIP00000012397	Bcl-2-like protein 11.	BCL2 family apoptosis regulator BOK b.	0.715
Bcl2l11	apaf1	ENSONIP00000042858	ENSONIP00000014380	Bcl-2-like protein 11.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.595
Bcl2l11	bad	ENSONIP00000042858	ENSONIP00000017011	Bcl-2-like protein 11.	BCL2 associated agonist of cell death b.	0.739
Bcl2l11	becn1	ENSONIP00000042858	ENSONIP00000020557	Bcl-2-like protein 11.	Beclin 1, autophagy related.	0.591
Bcl2l11	bmf	ENSONIP00000042858	ENSONIP00000015281	Bcl-2-like protein 11.	Uncharacterized protein.	0.582
LOC100692041	LOC100696271	ENSONIP00000073287	ENSONIP00000070141	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.901
LOC100692041	LOC100707238	ENSONIP00000073287	ENSONIP00000012397	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	BCL2 family apoptosis regulator BOK b.	0.492
LOC100692041	apaf1	ENSONIP00000073287	ENSONIP00000014380	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
LOC100692041	becn1	ENSONIP00000073287	ENSONIP00000020557	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Beclin 1, autophagy related.	0.430
LOC100696271	LOC100692041	ENSONIP00000070141	ENSONIP00000073287	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.901
LOC100696271	LOC100707238	ENSONIP00000070141	ENSONIP00000012397	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	BCL2 family apoptosis regulator BOK b.	0.492
LOC100696271	apaf1	ENSONIP00000070141	ENSONIP00000014380	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
LOC100696271	becn1	ENSONIP00000070141	ENSONIP00000020557	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Beclin 1, autophagy related.	0.430
LOC100707238	Bcl2l11	ENSONIP00000012397	ENSONIP00000042858	BCL2 family apoptosis regulator BOK b.	Bcl-2-like protein 11.	0.715
LOC100707238	LOC100692041	ENSONIP00000012397	ENSONIP00000073287	BCL2 family apoptosis regulator BOK b.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.492
LOC100707238	LOC100696271	ENSONIP00000012397	ENSONIP00000070141	BCL2 family apoptosis regulator BOK b.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.492
LOC100707238	apaf1	ENSONIP00000012397	ENSONIP00000014380	BCL2 family apoptosis regulator BOK b.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.515
LOC100707238	bad	ENSONIP00000012397	ENSONIP00000017011	BCL2 family apoptosis regulator BOK b.	BCL2 associated agonist of cell death b.	0.733
LOC100707238	becn1	ENSONIP00000012397	ENSONIP00000020557	BCL2 family apoptosis regulator BOK b.	Beclin 1, autophagy related.	0.624
LOC100707238	bmf	ENSONIP00000012397	ENSONIP00000015281	BCL2 family apoptosis regulator BOK b.	Uncharacterized protein.	0.543