Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100707238BCL2 family apoptosis regulator BOK b. (213 aa)    
Predicted Functional Partners:
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
     
  0.780
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
      
 0.721
morn3
MORN repeat containing 3.
      
 0.717
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
      
 0.711
Bcl2l11
Bcl-2-like protein 11.
    
 0.693
bad
BCL2 associated agonist of cell death b.
   
 0.645
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.601
becn1
Beclin 1, autophagy related.
    
 0.597
Tespa1
KRAP_IP3R_bind domain-containing protein.
    
   0.582
LOC100689723
BCL2 interacting protein 3 like b.
    
 0.559
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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