ENSONIP00000012427 protein (Oreochromis niloticus)

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ENSONIP00000012427

Autoimmune regulator. (369 aa)

Predicted Functional Partners:

LOC100711479

0.853

Kdm1a

0.832

LOC100706337

0.809

LOC100695351

0.809

mta2

0.796

LOC100696254

0.796

Mta1

0.796

gatad2b

0.780

LOC100694214

0.767

LOC100705552

0.767

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000012427	Kdm1a	ENSONIP00000012427	ENSONIP00000048588	Autoimmune regulator.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.832
ENSONIP00000012427	LOC100694214	ENSONIP00000012427	ENSONIP00000003069	Autoimmune regulator.	GATA zinc finger domain containing 2Ab.	0.767
ENSONIP00000012427	LOC100695351	ENSONIP00000012427	ENSONIP00000079377	Autoimmune regulator.	Retinoblastoma binding protein 4, like.	0.809
ENSONIP00000012427	LOC100696254	ENSONIP00000012427	ENSONIP00000045614	Autoimmune regulator.	Metastasis associated 1 family, member 3.	0.796
ENSONIP00000012427	LOC100705552	ENSONIP00000012427	ENSONIP00000012783	Autoimmune regulator.	GATA zinc finger domain containing 2A.	0.767
ENSONIP00000012427	LOC100706337	ENSONIP00000012427	ENSONIP00000038174	Autoimmune regulator.	WD_REPEATS_REGION domain-containing protein.	0.809
ENSONIP00000012427	LOC100711479	ENSONIP00000012427	ENSONIP00000070642	Autoimmune regulator.	Retinoblastoma binding protein 4.	0.853
ENSONIP00000012427	Mta1	ENSONIP00000012427	ENSONIP00000051134	Autoimmune regulator.	Metastasis associated 1.	0.796
ENSONIP00000012427	gatad2b	ENSONIP00000012427	ENSONIP00000013033	Autoimmune regulator.	GATA zinc finger domain containing 2B.	0.780
ENSONIP00000012427	mta2	ENSONIP00000012427	ENSONIP00000031611	Autoimmune regulator.	Metastasis associated 1 family, member 2.	0.796
Kdm1a	ENSONIP00000012427	ENSONIP00000048588	ENSONIP00000012427	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Autoimmune regulator.	0.832
Kdm1a	LOC100694214	ENSONIP00000048588	ENSONIP00000003069	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	GATA zinc finger domain containing 2Ab.	0.603
Kdm1a	LOC100695351	ENSONIP00000048588	ENSONIP00000079377	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Retinoblastoma binding protein 4, like.	0.877
Kdm1a	LOC100696254	ENSONIP00000048588	ENSONIP00000045614	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Metastasis associated 1 family, member 3.	0.844
Kdm1a	LOC100705552	ENSONIP00000048588	ENSONIP00000012783	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	GATA zinc finger domain containing 2A.	0.603
Kdm1a	LOC100706337	ENSONIP00000048588	ENSONIP00000038174	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	WD_REPEATS_REGION domain-containing protein.	0.877
Kdm1a	LOC100711479	ENSONIP00000048588	ENSONIP00000070642	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Retinoblastoma binding protein 4.	0.877
Kdm1a	Mta1	ENSONIP00000048588	ENSONIP00000051134	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Metastasis associated 1.	0.844
Kdm1a	gatad2b	ENSONIP00000048588	ENSONIP00000013033	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	GATA zinc finger domain containing 2B.	0.629
Kdm1a	mta2	ENSONIP00000048588	ENSONIP00000031611	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Metastasis associated 1 family, member 2.	0.844