Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100707807Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (367 aa)    
Predicted Functional Partners:
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
  
 0.940
I3JKS7_ORENI
PALP domain-containing protein.
  
 0.937
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.936
cth
Cystathionase (cystathionine gamma-lyase), like.
  
 0.911
LOC100701752
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.905
SDS
Serine dehydratase.
  
 0.894
LOC100705758
Serine dehydratase-like.
  
 0.894
LOC100694281
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.889
LOC100534427
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.889
LOC100702713
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.889
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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