Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cacybpCalcyclin binding protein. (227 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.995
siah1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.979
ENSONIP00000078800
annotation not available
    
 0.979
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 
 0.970
I3K8V7_ORENI
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.967
rnf41
Ring finger protein 41.
    
 
 0.907
LOC100707896
S100 calcium binding protein, beta (neural); Belongs to the S-100 family.
    
 
 0.801
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
   
 
 0.712
magoh
Mago homolog, exon junction complex subunit.
   
  
 0.709
stip1
Stress-induced phosphoprotein 1.
   
  
 0.686
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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