Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100709697UDENN domain-containing protein. (496 aa)    
Predicted Functional Partners:
map3k4
Mitogen-activated protein kinase kinase kinase 4.
    
   0.710
avl9
AVL9 homolog (S. cerevisiase).
      
 0.642
dennd10
DENN domain containing 10.
      
 0.638
dennd6a
DENN/MADD domain containing 6Aa.
      
 0.634
ighmbp2
Immunoglobulin mu DNA binding protein 2.
      
 0.502
Tgoln2
Trans-Golgi network integral membrane protein 2.
    
   0.485
pnkp
Polynucleotide kinase 3'-phosphatase.
   
  
 0.448
coasy
CoA synthase.
      
 0.445
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.409
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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