STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100692939Patched 2. (1433 aa)    
Predicted Functional Partners:
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.972
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.922
dhh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.900
LOC100706920
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.853
LOC100703074
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.853
gli1
GLI family zinc finger 1.
   
 0.822
boc
BOC cell adhesion associated, oncogene regulated.
    
 0.780
cdon
Cell adhesion associated, oncogene regulated.
    
 0.780
gli3
Uncharacterized protein.
   
 0.739
gli2
Uncharacterized protein.
   
 0.723
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.