rpap3 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

rpap3

RNA polymerase II associated protein 3. (663 aa)

Predicted Functional Partners:

ruvbl1

0.997

ruvbl2

0.994

ppp3r1

0.991

pih1d1

0.991

pfdn6

0.990

pdrg1

0.986

POLR2E

0.984

pfdn2

0.984

uxt

0.983

uri1

0.976

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
POLR2E	pdrg1	ENSONIP00000036615	ENSONIP00000052577	RNA polymerase II subunit E.	P53 and DNA-damage regulated 1.	0.962
POLR2E	pfdn2	ENSONIP00000036615	ENSONIP00000075419	RNA polymerase II subunit E.	Prefoldin subunit 2.	0.990
POLR2E	pfdn6	ENSONIP00000036615	ENSONIP00000045723	RNA polymerase II subunit E.	Prefoldin subunit 6.	0.923
POLR2E	pih1d1	ENSONIP00000036615	ENSONIP00000057276	RNA polymerase II subunit E.	PIH1 domain containing 1.	0.979
POLR2E	ppp3r1	ENSONIP00000036615	ENSONIP00000001534	RNA polymerase II subunit E.	WD repeat-containing protein 92.	0.949
POLR2E	rpap3	ENSONIP00000036615	ENSONIP00000012499	RNA polymerase II subunit E.	RNA polymerase II associated protein 3.	0.984
POLR2E	ruvbl1	ENSONIP00000036615	ENSONIP00000023970	RNA polymerase II subunit E.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.907
POLR2E	ruvbl2	ENSONIP00000036615	ENSONIP00000049031	RNA polymerase II subunit E.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.913
POLR2E	uri1	ENSONIP00000036615	ENSONIP00000013098	RNA polymerase II subunit E.	URI1 prefoldin like chaperone.	0.991
POLR2E	uxt	ENSONIP00000036615	ENSONIP00000077082	RNA polymerase II subunit E.	Ubiquitously-expressed, prefoldin-like chaperone.	0.981
pdrg1	POLR2E	ENSONIP00000052577	ENSONIP00000036615	P53 and DNA-damage regulated 1.	RNA polymerase II subunit E.	0.962
pdrg1	pfdn2	ENSONIP00000052577	ENSONIP00000075419	P53 and DNA-damage regulated 1.	Prefoldin subunit 2.	0.993
pdrg1	pfdn6	ENSONIP00000052577	ENSONIP00000045723	P53 and DNA-damage regulated 1.	Prefoldin subunit 6.	0.985
pdrg1	pih1d1	ENSONIP00000052577	ENSONIP00000057276	P53 and DNA-damage regulated 1.	PIH1 domain containing 1.	0.986
pdrg1	ppp3r1	ENSONIP00000052577	ENSONIP00000001534	P53 and DNA-damage regulated 1.	WD repeat-containing protein 92.	0.874
pdrg1	rpap3	ENSONIP00000052577	ENSONIP00000012499	P53 and DNA-damage regulated 1.	RNA polymerase II associated protein 3.	0.986
pdrg1	ruvbl1	ENSONIP00000052577	ENSONIP00000023970	P53 and DNA-damage regulated 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.893
pdrg1	ruvbl2	ENSONIP00000052577	ENSONIP00000049031	P53 and DNA-damage regulated 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.853
pdrg1	uri1	ENSONIP00000052577	ENSONIP00000013098	P53 and DNA-damage regulated 1.	URI1 prefoldin like chaperone.	0.976
pdrg1	uxt	ENSONIP00000052577	ENSONIP00000077082	P53 and DNA-damage regulated 1.	Ubiquitously-expressed, prefoldin-like chaperone.	0.989