Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tmem243Transmembrane protein 243, mitochondrial b. (117 aa)    
Predicted Functional Partners:
mfsd12
Major facilitator superfamily domain containing 12a.
      
 0.653
slc35f6
Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter.
      
 0.629
pih1d3
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
      
 0.621
lmbrd1
LMBR1 domain containing 1.
      
 0.582
ginm1
Glycoprotein integral membrane 1.
      
 0.564
tmem184c
Transmembrane protein 184C.
      
 0.522
I3JUG4_ORENI
Cyclin D binding myb-like transcription factor 1.
      
 0.428
Slc38a7
Solute carrier family 38 member 7.
      
 0.422
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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