STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgme1Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (346 aa)    
Predicted Functional Partners:
grsf1
G-rich RNA sequence binding factor 1.
    
 
 0.592
polg2
DNA polymerase subunit gamma-2, mitochondrial isoform X1.
      
 0.590
twnk
Twinkle mtDNA helicase.
      
 0.588
LOC100702602
Cytochrome c oxidase assembly factor 7.
      
 0.587
dna2
DNA replication helicase/nuclease 2.
   
  
 0.585
lg7h18orf54
Lung adenoma susceptibility protein 2.
      
 0.582
Mlh3
MutL homolog 3 (E. coli).
      
 0.581
carnmt1
Carnosine N-methyltransferase 1.
      
 0.570
Ecsit
ECSIT signalling integrator.
    
   0.523
pym1
PYM homolog 1, exon junction complex associated factor.
      
 0.503
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.