tpr protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tpr

Translocated promoter region b, nuclear basket protein. (2364 aa)

Predicted Functional Partners:

LOC100692890

0.974

nup107

0.935

nxf1

0.933

nup153

0.922

nup85

0.888

seh1l

0.872

nup93

0.871

nup205

0.870

nup133

0.861

nup155

0.848

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100692890	nup107	ENSONIP00000049343	ENSONIP00000022679	RAN binding protein 2.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.999
LOC100692890	nup133	ENSONIP00000049343	ENSONIP00000067094	RAN binding protein 2.	Nucleoporin 133.	0.999
LOC100692890	nup153	ENSONIP00000049343	ENSONIP00000003160	RAN binding protein 2.	Nucleoporin 153.	0.993
LOC100692890	nup155	ENSONIP00000049343	ENSONIP00000017656	RAN binding protein 2.	Nucleoporin 155.	0.999
LOC100692890	nup205	ENSONIP00000049343	ENSONIP00000012995	RAN binding protein 2.	Nucleoporin 205.	0.999
LOC100692890	nup85	ENSONIP00000049343	ENSONIP00000036473	RAN binding protein 2.	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).	0.999
LOC100692890	nup93	ENSONIP00000049343	ENSONIP00000057103	RAN binding protein 2.	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.	0.999
LOC100692890	nxf1	ENSONIP00000049343	ENSONIP00000035779	RAN binding protein 2.	Zgc:153681.	0.993
LOC100692890	seh1l	ENSONIP00000049343	ENSONIP00000046790	RAN binding protein 2.	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family.	0.997
LOC100692890	tpr	ENSONIP00000049343	ENSONIP00000012607	RAN binding protein 2.	Translocated promoter region b, nuclear basket protein.	0.974
nup107	LOC100692890	ENSONIP00000022679	ENSONIP00000049343	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	RAN binding protein 2.	0.999
nup107	nup133	ENSONIP00000022679	ENSONIP00000067094	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 133.	0.999
nup107	nup153	ENSONIP00000022679	ENSONIP00000003160	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 153.	0.980
nup107	nup155	ENSONIP00000022679	ENSONIP00000017656	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 155.	0.989
nup107	nup205	ENSONIP00000022679	ENSONIP00000012995	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 205.	0.997
nup107	nup85	ENSONIP00000022679	ENSONIP00000036473	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).	0.999
nup107	nup93	ENSONIP00000022679	ENSONIP00000057103	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.	0.997
nup107	nxf1	ENSONIP00000022679	ENSONIP00000035779	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Zgc:153681.	0.974
nup107	seh1l	ENSONIP00000022679	ENSONIP00000046790	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family.	0.999
nup107	tpr	ENSONIP00000022679	ENSONIP00000012607	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Translocated promoter region b, nuclear basket protein.	0.935