Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nr3c2Nuclear receptor subfamily 3, group C, member 2. (994 aa)    
Predicted Functional Partners:
LOC100534398
Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor).
  
 
0.926
NR3C1
Nuclear receptor subfamily 3 group C member 1.
    
 0.916
fkbp4
Peptidylprolyl isomerase.
    
 0.848
LOC100711482
Peptidylprolyl isomerase.
    
 0.848
hsd11b2
11-beta hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.807
pgr
Progesterone receptor.
     
 0.787
ace
Angiotensin-converting enzyme.
      
 0.755
agt
Angiotensinogen; Belongs to the serpin family.
      
 0.719
cyp11b
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
    
 0.706
carnmt1
Carnosine N-methyltransferase 1.
    
   0.701
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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