STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ism1Isthmin 1. (499 aa)    
Predicted Functional Partners:
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
   
 0.918
sptssa
Serine palmitoyltransferase small subunit A.
    
 0.777
sord
Sorbitol dehydrogenase.
  
 
 0.770
Kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.697
LOC100710995
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.619
ormdl1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.619
LOC100707365
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.619
sptssb
Serine palmitoyltransferase small subunit B isoform X1.
    
 0.618
adhfe1
Alcohol dehydrogenase iron containing 1.
    
 0.598
eprs1
Glutamyl-prolyl-tRNA synthetase.
   
 
 0.523
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.