STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btbd3BTB (POZ) domain containing 3b. (517 aa)    
Predicted Functional Partners:
cops3
COP9 signalosome subunit 3.
    
 0.628
cops2
COP9 signalosome subunit 2.
   
  0.620
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.613
LOC109194151
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.613
cul1
Cullin 1b; Belongs to the cullin family.
   
 0.609
cops5
COP9 signalosome subunit 5.
    
  0.603
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.569
ppp1r42
Protein phosphatase 1, regulatory subunit 42.
    
  0.566
cops8
COP9 signalosome subunit 8.
    
  0.548
COPS6
COP9 signalosome subunit 6.
    
  0.542
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.