Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CUL3Cullin 3; Belongs to the cullin family. (766 aa)    
Predicted Functional Partners:
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.988
kbtbd8
Kelch repeat and BTB (POZ) domain containing 8.
    
 0.977
cops5
COP9 signalosome subunit 5.
   
 0.975
klhl20
Kelch-like family member 20.
    
 0.974
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).
    
 0.972
klhl22
Kelch-like family member 22.
    
 0.968
cops2
COP9 signalosome subunit 2.
   
 0.968
kctd7
Potassium channel tetramerization domain containing 7.
    
 0.965
klhl8
Kelch-like family member 8.
    
 0.965
COPS6
COP9 signalosome subunit 6.
    
 0.962
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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