rfx2 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rfx2

Regulatory factor X, 2 (influences HLA class II expression). (736 aa)

Predicted Functional Partners:

atr

0.779

Chek2

0.630

MCIDAS

0.549

LOC100701716

0.538

LOC100703498

0.538

rfxap

0.517

klf9

0.492

SP3

0.489

LOC100693896

0.487

rfxank

0.432

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Chek2	atr	ENSONIP00000000942	ENSONIP00000000972	Checkpoint kinase 2.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.996
Chek2	rfx2	ENSONIP00000000942	ENSONIP00000012630	Checkpoint kinase 2.	Regulatory factor X, 2 (influences HLA class II expression).	0.630
LOC100693896	SP3	ENSONIP00000002768	ENSONIP00000010894	Ets variant 2.	Sp3a transcription factor.	0.487
LOC100693896	klf9	ENSONIP00000002768	ENSONIP00000014842	Ets variant 2.	Kruppel-like factor 9.	0.493
LOC100693896	rfx2	ENSONIP00000002768	ENSONIP00000012630	Ets variant 2.	Regulatory factor X, 2 (influences HLA class II expression).	0.487
LOC100701716	MCIDAS	ENSONIP00000041803	ENSONIP00000021448	Forkhead box J1a.	Uncharacterized protein.	0.439
LOC100701716	rfx2	ENSONIP00000041803	ENSONIP00000012630	Forkhead box J1a.	Regulatory factor X, 2 (influences HLA class II expression).	0.538
LOC100703498	MCIDAS	ENSONIP00000080635	ENSONIP00000021448	Forkhead box J1b.	Uncharacterized protein.	0.439
LOC100703498	rfx2	ENSONIP00000080635	ENSONIP00000012630	Forkhead box J1b.	Regulatory factor X, 2 (influences HLA class II expression).	0.538
MCIDAS	LOC100701716	ENSONIP00000021448	ENSONIP00000041803	Uncharacterized protein.	Forkhead box J1a.	0.439
MCIDAS	LOC100703498	ENSONIP00000021448	ENSONIP00000080635	Uncharacterized protein.	Forkhead box J1b.	0.439
MCIDAS	rfx2	ENSONIP00000021448	ENSONIP00000012630	Uncharacterized protein.	Regulatory factor X, 2 (influences HLA class II expression).	0.549
SP3	LOC100693896	ENSONIP00000010894	ENSONIP00000002768	Sp3a transcription factor.	Ets variant 2.	0.487
SP3	rfx2	ENSONIP00000010894	ENSONIP00000012630	Sp3a transcription factor.	Regulatory factor X, 2 (influences HLA class II expression).	0.489
atr	Chek2	ENSONIP00000000972	ENSONIP00000000942	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint kinase 2.	0.996
atr	rfx2	ENSONIP00000000972	ENSONIP00000012630	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Regulatory factor X, 2 (influences HLA class II expression).	0.779
klf9	LOC100693896	ENSONIP00000014842	ENSONIP00000002768	Kruppel-like factor 9.	Ets variant 2.	0.493
klf9	rfx2	ENSONIP00000014842	ENSONIP00000012630	Kruppel-like factor 9.	Regulatory factor X, 2 (influences HLA class II expression).	0.492
rfx2	Chek2	ENSONIP00000012630	ENSONIP00000000942	Regulatory factor X, 2 (influences HLA class II expression).	Checkpoint kinase 2.	0.630
rfx2	LOC100693896	ENSONIP00000012630	ENSONIP00000002768	Regulatory factor X, 2 (influences HLA class II expression).	Ets variant 2.	0.487