STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JUV2_ORENISpastin; Belongs to the AAA ATPase family. (495 aa)    
Predicted Functional Partners:
I3J4H0_ORENI
IST1 factor associated with ESCRT-III.
    
 0.966
atl1
Atlastin GTPase 1.
   
 
 0.932
I3KW68_ORENI
Receptor expression-enhancing protein.
   
 
 0.880
lg23h1orf112
Si:dkey-97o5.1.
   
 0.853
LOC100702665
Uncharacterized protein.
    
 0.837
chmp1b
Chromatin modifying protein 1B.
    
 0.837
ubxn7
UBX domain protein 7.
   
 0.807
SPIDR
Uncharacterized protein.
    
 0.778
LOC100707350
Atlastin 3.
   
 
 0.763
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.751
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.