Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100701197Calponin-homology (CH) domain-containing protein. (1802 aa)    
Predicted Functional Partners:
I3KFA3_ORENI
Afadin, adherens junction formation factor a.
   
  0.591
ENSONIP00000048171
annotation not available
   
  0.591
mff
Mitochondrial fission factor.
    
 0.582
thyn1
Thymocyte nuclear protein 1.
      
 0.573
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
   0.549
actn3
Actinin alpha 3b.
   
 
 0.543
LOC100696265
Actinin, alpha 1.
   
 
 0.543
LOC100702502
Actinin, alpha 2b.
   
 
 0.543
ACTN4
Actinin alpha 4.
   
 
 0.543
LOC102077079
Uncharacterized protein.
  
 
   0.466
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.