STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eef1akmt4Endothelin converting enzyme 2a. (244 aa)    
Predicted Functional Partners:
LOC102082288
Endothelin-1.
      
 0.721
mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.560
ednra
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.476
cs
Citrate synthase; Belongs to the citrate synthase family.
    
 0.464
pam
Peptidylglycine alpha-amidating monooxygenase.
      
 0.444
LOC100698078
Si:dkey-288i20.2.
      
 0.442
GPR139
G protein-coupled receptor 139.
      
 0.442
I3JBF9_ORENI
Amyloid beta precursor protein binding family B member 2.
      
 0.441
LOC100693961
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b.
    
 0.433
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2.
    
 0.433
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.