Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
LOC100699081Mitochondrial E3 ubiquitin protein ligase 1a. (344 aa)    
Predicted Functional Partners:
Mfn2
Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.606
ubxn7
UBX domain protein 7.
    
 0.596
p53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
   0.556
tomm70
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
     
 0.541
usp30
Ubiquitin carboxyl-terminal hydrolase.
     
 0.524
fkbp8
Peptidylprolyl isomerase.
     
 0.515
LOC100692597
Peptidylprolyl isomerase.
     
 0.515
gabarap
Gamma-aminobutyric acid receptor-associated protein.
    
 0.512
LOC100690483
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
     
 0.510
rhot2
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
     
 0.510
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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