Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100692580Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (309 aa)    
Predicted Functional Partners:
ano6
Anoctamin.
      
 0.646
pum1
Pumilio RNA-binding family member 1.
    
 
 0.619
Clcc1
Uncharacterized protein.
    
 
 0.604
LOC100693800
SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.
    
 
 0.604
plekhn1
Pleckstrin homology domain containing, family N member 1.
    
 
 0.580
I3IW97_ORENI
TUB like protein 4b; Belongs to the TUB family.
      
 0.469
LOC100706477
XK-related protein.
      
 0.453
COX1
Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
    
 
 0.437
ano3
Anoctamin.
      
 0.410
LOC100702954
Interferon regulatory factor 3.
      
 0.410
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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