Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
I3JWG9_ORENINuclear receptor subfamily 2, group F, member 6a. (390 aa)    
Predicted Functional Partners:
Bola1
BolA family member 1; Belongs to the BolA/IbaG family.
      
 0.784
LOC100696049
Anoctamin.
      
 0.727
adam9
Disintegrin and metalloproteinase domain-containing protein 9 isoform X1.
      
 0.646
ano8
Anoctamin.
      
 0.635
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.629
plvap
Plasmalemma vesicle associated protein b.
    
 0.615
I3JWH2_ORENI
Plasmalemma vesicle associated protein a.
    
 0.615
ncor2
Nuclear receptor corepressor 2.
    
 0.559
ncor1
Nuclear receptor corepressor 1.
    
 0.559
I3K328_ORENI
TEA domain-containing protein.
      
 0.551
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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