Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
babam1BRISC and BRCA1 A complex member 1. (378 aa)    
Predicted Functional Partners:
brcc3
BRCA1/BRCA2-containing complex, subunit 3.
    
 0.999
babam2
BRISC and BRCA1 A complex member 2.
    
 0.999
abraxas2
Abraxas 2, BRISC complex subunit.
    
 0.999
brca1
Uncharacterized protein.
    
 0.996
bard1
BRCA1 associated RING domain 1.
    
 0.988
Uimc1
Uncharacterized protein.
    
 0.976
lg12h9orf85
Zgc:101016.
    
   0.894
mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.806
psmd14
Proteasome 26S subunit, non-ATPase 14.
    
 0.790
mpnd
MPN domain containing.
    
 0.790
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]