Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
klhl2Kelch-like family member 2. (605 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.875
LOC109194151
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.875
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.774
fbxl17
F-box and leucine-rich repeat protein 17.
    
 0.736
Nanp
N-acetylneuraminic acid phosphatase.
   
 
 0.686
Sec13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 
 0.675
cand1
Cullin-associated and neddylation-dissociated 1.
     
 0.674
I3JCU3_ORENI
TIP120 domain-containing protein.
     
 0.674
ubxn7
UBX domain protein 7.
    
  0.666
sec31a
SEC31 homolog A, COPII coat complex component.
    
 
 0.657
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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