STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpeCarboxypeptidase E. (469 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
    
  0.937
pcsk2
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
   
  
 0.704
LOC100699903
Carboxypeptidase B2 (plasma).
     
 0.699
chga
Uncharacterized protein.
      
 0.575
ins
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.537
LOC100704156
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.537
ENSONIP00000040127
annotation not available
     
 0.537
Tmprss9
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  
 0.529
tmprss2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
   
  
 0.522
scg3
Secretogranin III.
   
  
 0.507
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]