cpe protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

cpe

Carboxypeptidase E. (469 aa)

Predicted Functional Partners:

LOC100699903

0.826

pcsk2

0.707

I3KKT2_ORENI

0.693

nagk

0.689

pam

0.652

scg3

0.634

pcsk1

0.624

LOC102079407

0.624

ins

0.604

LOC100704156

0.604

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3KKT2_ORENI	cpe	ENSONIP00000064430	ENSONIP00000012727	Signal peptidase complex subunit 2.	Carboxypeptidase E.	0.693
I3KKT2_ORENI	pam	ENSONIP00000064430	ENSONIP00000051193	Signal peptidase complex subunit 2.	Peptidylglycine alpha-amidating monooxygenase.	0.413
LOC100699903	cpe	ENSONIP00000015401	ENSONIP00000012727	Carboxypeptidase B2 (plasma).	Carboxypeptidase E.	0.826
LOC100704156	LOC102079407	ENSONIP00000022171	ENSONIP00000052844	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Furin-like protease kpc-1 isoform X1.	0.674
LOC100704156	cpe	ENSONIP00000022171	ENSONIP00000012727	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Carboxypeptidase E.	0.604
LOC100704156	pam	ENSONIP00000022171	ENSONIP00000051193	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Peptidylglycine alpha-amidating monooxygenase.	0.443
LOC100704156	pcsk1	ENSONIP00000022171	ENSONIP00000034968	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.674
LOC100704156	pcsk2	ENSONIP00000022171	ENSONIP00000064419	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.	0.680
LOC102079407	LOC100704156	ENSONIP00000052844	ENSONIP00000022171	Furin-like protease kpc-1 isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.674
LOC102079407	cpe	ENSONIP00000052844	ENSONIP00000012727	Furin-like protease kpc-1 isoform X1.	Carboxypeptidase E.	0.624
LOC102079407	ins	ENSONIP00000052844	ENSONIP00000000431	Furin-like protease kpc-1 isoform X1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.674
cpe	I3KKT2_ORENI	ENSONIP00000012727	ENSONIP00000064430	Carboxypeptidase E.	Signal peptidase complex subunit 2.	0.693
cpe	LOC100699903	ENSONIP00000012727	ENSONIP00000015401	Carboxypeptidase E.	Carboxypeptidase B2 (plasma).	0.826
cpe	LOC100704156	ENSONIP00000012727	ENSONIP00000022171	Carboxypeptidase E.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.604
cpe	LOC102079407	ENSONIP00000012727	ENSONIP00000052844	Carboxypeptidase E.	Furin-like protease kpc-1 isoform X1.	0.624
cpe	ins	ENSONIP00000012727	ENSONIP00000000431	Carboxypeptidase E.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.604
cpe	nagk	ENSONIP00000012727	ENSONIP00000053624	Carboxypeptidase E.	Meiosis 1 associated protein.	0.689
cpe	pam	ENSONIP00000012727	ENSONIP00000051193	Carboxypeptidase E.	Peptidylglycine alpha-amidating monooxygenase.	0.652
cpe	pcsk1	ENSONIP00000012727	ENSONIP00000034968	Carboxypeptidase E.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.624
cpe	pcsk2	ENSONIP00000012727	ENSONIP00000064419	Carboxypeptidase E.	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.	0.707