Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000012749annotation not available (1687 aa)    
Predicted Functional Partners:
LOC100711605
Malate synthase-like.
   
 
 0.732
tubgcp2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
    
 0.702
kars1
Lysine--tRNA ligase.
    
   0.598
lars1
Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.579
tubg1
Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
   
 
 0.575
espl1
Extra spindle pole bodies like 1, separase.
   
 0.562
tubgcp3
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
    
 0.539
plk3
Serine/threonine-protein kinase PLK.
   
 0.532
plk2
Serine/threonine-protein kinase PLK.
   
 0.532
plk1
Serine/threonine-protein kinase PLK.
   
 0.532
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (34%) [HD]