Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
frg1FSHD region gene 1. (255 aa)    
Predicted Functional Partners:
Cwc22
MI domain-containing protein.
   
   0.966
prpf8
Pre-mRNA processing factor 8.
    
 
 0.874
snrpd3
Small nuclear ribonucleoprotein Sm D3.
   
 
 0.785
Snrpf
Small nuclear ribonucleoprotein F.
    
 
 0.766
snrpe
Small nuclear ribonucleoprotein E.
   
   0.766
prpf19
Pre-mRNA processing factor 19.
    
   0.762
cdc40
Cell division cycle 40 homolog (S. cerevisiae).
    
   0.760
ppil1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.759
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 
 0.759
plrg1
Pleiotropic regulator 1.
    
   0.759
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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