Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100696319Ring finger protein 126. (311 aa)    
Predicted Functional Partners:
get4
Guided entry of tail-anchored proteins factor 4.
   
 
 0.934
get3
ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
    
 
 0.855
LOC100694839
BCL2 associated athanogene 6, like.
    
 
 0.793
bag6
BCL2 associated athanogene 6.
    
 
 0.793
ENSONIP00000058229
Large proline-rich protein BAG6 isoform X1.
    
 
 0.793
rspo2
R-spondin 2.
    
 0.664
ENSONIP00000047919
Ubiquitin B.
    
  0.659
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.650
LOC100691476
Ubiquitin-like protein 4A.
    
 0.640
faf2
Fas associated factor family member 2.
    
 
 0.608
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]