Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JVB1_ORENILecithin retinol acyltransferase a. (228 aa)    
Predicted Functional Partners:
retsat
Retinol saturase (all-trans-retinol 13,14-reductase).
     
 0.958
LOC100695684
Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.956
rdh10
Retinol dehydrogenase 10a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.948
LOC100690880
Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.948
LOC100702412
Retinoid isomerohydrolase RPE65 a.
     
 0.946
LOC100694376
Retinoid isomerohydrolase RPE65 b.
     
 0.946
rdh5
Retinol dehydrogenase 5 (11-cis/9-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.939
dhrs3
Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.936
I3JGF1_ORENI
Uncharacterized protein.
     
 0.933
LOC100709359
Si:ch1073-13h15.3.
     
 0.933
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]