Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
I3JVD4_ORENIHeat shock transcription factor 4. (404 aa)    
Predicted Functional Partners:
Hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
    
 0.864
LOC100701982
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 0.864
ENSONIP00000075873
Heat shock factor binding protein 1a.
    
 0.800
LOC100707311
Heat shock cognate 70; Belongs to the heat shock protein 70 family.
    
 0.750
sirt1
Deacetylase sirtuin-type domain-containing protein.
   
 0.735
ENSONIP00000027324
Heat shock 70kDa protein 1/2/6/8.
    
 0.725
HSPA8
Uncharacterized protein.
    
 0.725
LOC100696748
Uncharacterized protein; Belongs to the heat shock protein 70 family.
    
 0.725
ENSONIP00000078834
Heat shock 70kDa protein 1/2/6/8.
    
 0.725
hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1.
   
 
 0.720
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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