LOC100698109 protein (Oreochromis niloticus)

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LOC100698109

Methyl-CpG binding domain protein 3. (239 aa)

Predicted Functional Partners:

LOC100708236

0.866

LOC100701661

0.866

mta2

0.845

LOC100696254

0.845

Mta1

0.845

LOC100706337

0.814

LOC100711479

0.814

LOC100695351

0.814

Kdm1a

0.772

LOC100705962

0.761

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kdm1a	LOC100695351	ENSONIP00000048588	ENSONIP00000079377	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Retinoblastoma binding protein 4, like.	0.877
Kdm1a	LOC100696254	ENSONIP00000048588	ENSONIP00000045614	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Metastasis associated 1 family, member 3.	0.844
Kdm1a	LOC100698109	ENSONIP00000048588	ENSONIP00000012845	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Methyl-CpG binding domain protein 3.	0.772
Kdm1a	LOC100701661	ENSONIP00000048588	ENSONIP00000065913	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Methyl-CpG-binding domain protein 3 isoform X1.	0.842
Kdm1a	LOC100705962	ENSONIP00000048588	ENSONIP00000008816	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Chromodomain helicase DNA binding protein 4a.	0.832
Kdm1a	LOC100706337	ENSONIP00000048588	ENSONIP00000038174	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	WD_REPEATS_REGION domain-containing protein.	0.877
Kdm1a	LOC100708236	ENSONIP00000048588	ENSONIP00000015903	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Methyl-CpG binding domain protein 2.	0.842
Kdm1a	LOC100711479	ENSONIP00000048588	ENSONIP00000070642	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Retinoblastoma binding protein 4.	0.877
Kdm1a	Mta1	ENSONIP00000048588	ENSONIP00000051134	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Metastasis associated 1.	0.844
Kdm1a	mta2	ENSONIP00000048588	ENSONIP00000031611	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Metastasis associated 1 family, member 2.	0.844
LOC100695351	Kdm1a	ENSONIP00000079377	ENSONIP00000048588	Retinoblastoma binding protein 4, like.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.877
LOC100695351	LOC100696254	ENSONIP00000079377	ENSONIP00000045614	Retinoblastoma binding protein 4, like.	Metastasis associated 1 family, member 3.	0.861
LOC100695351	LOC100698109	ENSONIP00000079377	ENSONIP00000012845	Retinoblastoma binding protein 4, like.	Methyl-CpG binding domain protein 3.	0.814
LOC100695351	LOC100701661	ENSONIP00000079377	ENSONIP00000065913	Retinoblastoma binding protein 4, like.	Methyl-CpG-binding domain protein 3 isoform X1.	0.848
LOC100695351	LOC100705962	ENSONIP00000079377	ENSONIP00000008816	Retinoblastoma binding protein 4, like.	Chromodomain helicase DNA binding protein 4a.	0.809
LOC100695351	LOC100708236	ENSONIP00000079377	ENSONIP00000015903	Retinoblastoma binding protein 4, like.	Methyl-CpG binding domain protein 2.	0.848
LOC100695351	Mta1	ENSONIP00000079377	ENSONIP00000051134	Retinoblastoma binding protein 4, like.	Metastasis associated 1.	0.861
LOC100695351	mta2	ENSONIP00000079377	ENSONIP00000031611	Retinoblastoma binding protein 4, like.	Metastasis associated 1 family, member 2.	0.861
LOC100696254	Kdm1a	ENSONIP00000045614	ENSONIP00000048588	Metastasis associated 1 family, member 3.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.844
LOC100696254	LOC100695351	ENSONIP00000045614	ENSONIP00000079377	Metastasis associated 1 family, member 3.	Retinoblastoma binding protein 4, like.	0.861