Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
I3JVK6_ORENIMatrix metallopeptidase 15a. (640 aa)    
Predicted Functional Partners:
LOC102081483
Ubiquitin-conjugating enzyme E2 variant 1.
     
  0.600
LOC100702284
TIMP metallopeptidase inhibitor 2b.
   
 0.582
timp2
TIMP metallopeptidase inhibitor 2a.
   
 0.582
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.582
I3KB63_ORENI
Link domain-containing protein.
    
 0.473
I3JMW5_ORENI
BZIP domain-containing protein.
      
 0.471
ccni
Cyclin I; Belongs to the cyclin family.
     
 0.450
pla2g4a
Phospholipase A2.
     
  0.423
dcn
Decorin; May affect the rate of fibrils formation.
   
 0.423
kitlg
Kit ligand a.
     
 0.415
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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